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ilar¡¡conclusions¡¡were¡¡reached¡¡also¡¡by¡¡Dr¡£¡¡Hughlings¡­Jackson£»¡¡in¡¡England£»¡¡from¡¡his¡¡studies¡¡of¡¡epilepsy¡£¡¡But¡¡no¡¡positive¡¡evidence¡¡was¡¡forthcoming¡¡until¡¡1861£»¡¡when¡¡Dr¡£¡¡Paul¡¡Broca¡¡brought¡¡before¡¡the¡¡Academy¡¡of¡¡Medicine¡¡in¡¡Paris¡¡a¡¡case¡¡of¡¡brain¡¡lesion¡¡which¡¡he¡¡regarded¡¡as¡¡having¡¡most¡¡important¡¡bearings¡¡on¡¡the¡¡question¡¡of¡¡cerebral¡¡localization¡£

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Special¡¡methods£»¡¡therefore£»¡¡were¡¡needed¡¡for¡¡this¡¡essay£»¡¡and¡¡brain¡¡histology¡¡has¡¡progressed¡¡by¡¡fitful¡¡impulses£»¡¡each¡¡forward¡¡jet¡¡marking¡¡the¡¡introduction¡¡of¡¡some¡¡ingenious¡¡improvement¡¡of¡¡mechanical¡¡technique£»¡¡which¡¡placed¡¡a¡¡new¡¡weapon¡¡in¡¡the¡¡hands¡¡of¡¡the¡¡investigators¡£

The¡¡very¡¡beginning¡¡was¡¡made¡¡in¡¡1824¡¡by¡¡Rolando£»¡¡who¡¡first¡¡thought¡¡of¡¡cutting¡¡chemically¡¡hardened¡¡pieces¡¡of¡¡brain¡¡tissues¡¡into¡¡thin¡¡sections¡¡for¡¡microscopical¡¡examinationthe¡¡basal¡¡structure¡¡upon¡¡which¡¡almost¡¡all¡¡the¡¡later¡¡advances¡¡have¡¡been¡¡conducted¡£¡¡Muller¡¡presently¡¡discovered¡¡that¡¡bichromate¡¡of¡¡potassium¡¡in¡¡solution¡¡makes¡¡the¡¡best¡¡of¡¡fluids¡¡for¡¡the¡¡preliminary¡¡preservation¡¡and¡¡hardening¡¡of¡¡the¡¡tissues¡£¡¡¡¡Stilling£»¡¡in¡¡1842£»¡¡perfected¡¡th

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